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直接植入式乳房重建:91例连续病例的回顾性分析。

Direct-to-implant breast reconstruction: retrospective analysis of 91 consecutive cases.

作者信息

Masciopinto Giuseppe, Brambullo Tito, Marchet Alberto, Varotto Andrea, Marini Massimo, Azzena Gian Paolo, Fanton Gloria, Vindigni Vincenzo

机构信息

Plastic Surgery Unit, Department of Neurosciences, University of Padua, via Giustiniani 2, Padova, Veneto, Italy.

Breast Surgery Unit, Veneto Institute of Oncology, Padova, Italy.

出版信息

Updates Surg. 2025 Oct 14. doi: 10.1007/s13304-025-02425-5.

Abstract

Implant-based reconstruction is the main post-mastectomy reconstructive method. With the introduction of acellular dermal matrices (ADM), direct-to-implant reconstruction has, in selected patients, replaced dual-stage technique with tissue expander. The objective of this study is to compare postoperative outcomes and quality of life of three DTI breast reconstruction techniques: pre-pectoral with ADM versus submuscular without ADM versus submuscular with ADM (dual plane). A retrospective study was conducted between January 2020 and April 2023. The enrolled patients were divided into three groups: patients who underwent mastectomy and pre-pectoral reconstruction with ADM (group A); patients treated with submuscular reconstruction without ADM (group B); and patients who underwent submuscular reconstruction with ADM (group C). Minor and major complications, revision rates, and capsular contracture rates were recorded, and patients underwent the BRECON-31 postoperative questionnaire. A total of 27 pre-pectoral reconstructions with ADM, 41 submuscular reconstructions without ADM, and 23 dual-plane reconstructions with ADM were performed. The incidence of major complications (p = 0.076) and severe capsular contracture (p = 0.048) was higher in group C. Group C achieved lower results than other groups for all BRECON-31 categories except for Recovery category. According to the study findings, the direct-to-implant breast reconstruction showed to be effective; however, the pre-pectoral technique with ADM does not seem to have superiority over the conventional muscle-pocket technique in terms of reducing complication rate and overall patient satisfaction.Level of evidence: 4.

摘要

基于植入物的重建是乳房切除术后主要的重建方法。随着脱细胞真皮基质(ADM)的引入,在部分患者中,直接植入式重建已取代了使用组织扩张器的两阶段技术。本研究的目的是比较三种直接植入式乳房重建技术的术后结果和生活质量:带ADM的胸肌前重建与不带ADM的胸肌下重建与带ADM的胸肌下重建(双平面)。在2020年1月至2023年4月期间进行了一项回顾性研究。纳入的患者分为三组:接受乳房切除术并采用带ADM的胸肌前重建的患者(A组);接受不带ADM的胸肌下重建的患者(B组);以及接受带ADM的胸肌下重建的患者(C组)。记录轻微和严重并发症、翻修率和包膜挛缩率,患者接受BRECON - 31术后问卷。共进行了27例带ADM的胸肌前重建、41例不带ADM的胸肌下重建和23例带ADM的双平面重建。C组的严重并发症发生率(p = 0.076)和严重包膜挛缩发生率(p = 0.048)较高。除恢复类别外,C组在所有BRECON - 31类别中的结果均低于其他组。根据研究结果,直接植入式乳房重建显示出有效;然而,在降低并发症发生率和总体患者满意度方面,带ADM的胸肌前技术似乎并不优于传统的肌袋技术。证据级别:4。

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