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捷克斯洛伐克ACP01等位基因的出现情况。

Occurrence of the ACP01 allele in Czechoslovakia.

作者信息

Nezbeda P

出版信息

Hum Genet. 1979 Jan 25;46(2):227-9. doi: 10.1007/BF00291925.

Abstract

During a paternity test an unexpected type of red cell acid phosphatase isozyme (ACP1) was found in one family. The mother was of type A and type B was diagnosed in the son. The whole family was then subjected to ACP1 phenotyping and to the enzyme assay. Five members of the family were found to have unexpected types of ACP1 isozymes. The average activity was approx. 50% of normal values. It is presumed that a silent ACP01 allele was found in the family investigated and that the grandfather was its first carrier.

摘要

在一次亲子鉴定中,在一个家庭里发现了一种意外类型的红细胞酸性磷酸酶同工酶(ACP1)。母亲为A型,儿子被诊断为B型。随后对整个家庭进行了ACP1表型分析和酶活性测定。该家庭的五名成员被发现具有意外类型的ACP1同工酶。平均活性约为正常值的50%。据推测,在所调查的家庭中发现了一个沉默的ACP01等位基因,并且祖父是其首个携带者。

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