Taha H M, Al-Obeidi F A, Borazan H N
J Pharm Sci. 1979 May;68(5):631-3. doi: 10.1002/jps.2600680532.
Charge transfer complex formation between nucleic acid bases and isoproterenol was demonstrated from UV absorption measurements. The solvent polarity effects on equilibrium constants were investigated. The solvent systems containing 0.1 N HCl were 20% aqueous ethanol, water, and water containing sodium chloride. The equilibrium constants, calculated from UV absorption data by the application of the Benesi-Hildebrand equation, were small and increased with increasing ionic strength. Equilibrium constant wavelength dependence was demonstrated in some cases.
