Ishiyama I, Nagai T, Nagai T, Komuro E, Momose T, Akimori N
Z Rechtsmed. 1979 Mar 8;82(4):251-6. doi: 10.1007/BF02092036.
Morphine and methamphetamine, which are excreted in the sweat, are detected by the use of routine serological and physicochemical techniques for urinary examinations. Screening for drug abuse can be done with the same accuracy of that of urine. Rapid excretion of the drug via kidney (within one day) is followed by a slow but steady excretion of the sweat gland. Methamphetamine given orally in a dose of 10 mg is excreted in the sweat at a constant rate (1.4 microgram/ml). No significant difference of the amount excreted by both systems is found. Alveolar lining seems to prevent the elimination of the volatile methamphetamine via respiration. Not only narcotics and stimulants, but also many alkaloids and barbituarates are excreted in the sweat and detected quantitatively by the same principles. The toxicological analysis of the sweat promises a new scope of forensic investigation.
吗啡和甲基苯丙胺可通过用于尿液检测的常规血清学和物理化学技术在汗液中被检测到，它们可经汗液排出。药物滥用筛查的准确率与尿液检测相同。药物经肾脏快速排泄（一天内）后，汗腺会缓慢但持续地排泄。口服10毫克甲基苯丙胺后，汗液中会以恒定速率（1.4微克/毫升）排泄。两个系统的排泄量未发现显著差异。肺泡衬里似乎可防止挥发性甲基苯丙胺通过呼吸排出。不仅麻醉品和兴奋剂，许多生物碱和巴比妥酸盐也可经汗液排出，并按照相同原理进行定量检测。汗液的毒理学分析为法医调查开辟了新的领域。
