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结节病所致支气管狭窄:一种可导致肺不张和气道阻塞的病因,易误诊为肺部肿瘤和慢性阻塞性肺疾病。

Bronchostenosis due to sarcoidosis: a cause of atelectasis and airway obstruction simulating pulmonary neoplasm and chronic obstructive pulmonary disease.

作者信息

Olsson T, Björnstad-Pettersen H, Stjernberg N L

出版信息

Chest. 1979 Jun;75(6):663-6. doi: 10.1378/chest.75.6.663.

Abstract

Ninety-nine patients with clinically and histopathologically established sarcoidosis were studied during the period of January 1971 to October 1977 using the bronchoscope. In 32 patients, biopsy of the bronchial mucosa showed a microscopic picture typical of sarcoidosis. In eight (8 percent) of the 99 patients, severe stenosis of the bronchi was seen. We conclude that bronchial sarcoidosis with multiple segmental or lobar stenosis can closely imitate the clinical picture of chronic obstructive pulmonary disease. Bronchostenosis in sarcoidosis can cause atelectasis visible on the chest x-ray film and thus closely simulate a pulmonary neoplasm.

摘要

1971年1月至1977年10月期间,对99例临床和组织病理学确诊的结节病患者进行了支气管镜检查。32例患者的支气管黏膜活检显示出结节病典型的微观图像。在这99例患者中,有8例(8%)出现了严重的支气管狭窄。我们得出结论,伴有多节段或大叶狭窄的支气管结节病可酷似慢性阻塞性肺疾病的临床表现。结节病中的支气管狭窄可导致胸部X线片上可见肺不张,从而酷似肺部肿瘤。

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