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在人小肠液中孵育的市售胰酶制剂的胰腺酶活性。

Pancreatic enzymic activities of commercial pancreatic enzyme preparations incubated in human small intestinal juice.

作者信息

Ihse I, Lilja P

出版信息

Digestion. 1979;19(1):48-51. doi: 10.1159/000198321.

DOI:10.1159/000198321
PMID:456768
Abstract

The activities of amylase, lipase, phospholipase and trypsin of twelve commercial pancreatic enzyme preparations were measured under identical conditions. Human small intestinal juice was chosen as incubation medium. A wide variation of enzymatic activities was found in preparations in tablet form contrary to preparations in granulated form. A prerequisite for a successful therapy is enzymically potent pancreatic extracts with high enzyme content per table, capsule or recommended dose of granulated preparation. Therefore, some preparations seem to be preferable to others for clinical purposes.

摘要

在相同条件下测定了12种市售胰酶制剂的淀粉酶、脂肪酶、磷脂酶和胰蛋白酶活性。选用人小肠液作为孵育介质。与颗粒剂形式的制剂相反,片剂形式的制剂中酶活性存在很大差异。成功治疗的一个前提是酶活性强的胰提取物,每片、每粒胶囊或推荐剂量的颗粒剂制剂中酶含量高。因此,出于临床目的,某些制剂似乎比其他制剂更可取。

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