麻风分枝杆菌与其原始宿主之间的病理生物学关系。
Pathobiological relationships between Mycobacterium leprae and its primitive host.
作者信息
Kwapinski J B, Kwapinski E H
出版信息
Bull World Health Organ. 1974;50(5):473-4.
Newborn snakes were injected with 10(2)-10(4) live or heated Mycobacterium leprae. Death occurred in 5-6 weeks. On autopsy, the snakes injected with live microorganisms showed pathological changes and numerous acid-fast bacteria were found in some organs. Material was also transferred from an experimentally infected snake to a group of normal newborn snakes, causing their death in 3 weeks. Extracts in phosphate-buffered saline, prepared from the tissues of infected snakes, were found to react with anti-M. leprae and anti-M. lepraemurium rabbit antisera. No immunodiffusion reactions were elicited by extracts from the organs of control snakes.
给新生蛇注射10²-10⁴个活的或加热过的麻风分枝杆菌。5-6周后死亡。尸检时，注射了活微生物的蛇呈现出病理变化，在一些器官中发现了大量抗酸菌。还将材料从一条实验感染的蛇转移到一组正常新生蛇身上，导致它们在3周内死亡。发现从感染蛇的组织中制备的磷酸盐缓冲盐水提取物能与抗麻风分枝杆菌和抗鼠麻风分枝杆菌兔抗血清发生反应。对照蛇器官的提取物未引发免疫扩散反应。
Zotero 插件