人体脂肪组织游离脂肪酸释放与肥胖的关系——异丙肾上腺素的作用
Free fatty acid release from human adipose tissue in relation to obesity -- effect of isoprenaline.
作者信息
Rath R, Wenkeová J
出版信息
Endokrinologie. 1979 Feb;73(1):91-6.
The capacity to release non-esterified acids and glycerol from the abdominal subcutaneous adipose tissue into a medium containing different concentrations of isoprenaline was studied in 21 adults with different body weight (14 obese, 7 controls). The obese had a significantly lower maximum adipokinetic capacity (expressed as pD2) than controls. The significant decrease in pD2 in the obese was found to depend on the stabilization of the weight while the dynamic pD2 stage values of the obese did not differ from those of controls. The hypothesis is expressed that lower pD2 values may be related to the smaller decrease of body fat during weight reduction.
在21名体重各异的成年人（14名肥胖者，7名对照者）中，研究了腹部皮下脂肪组织将非酯化酸和甘油释放到含有不同浓度异丙肾上腺素的培养基中的能力。肥胖者的最大脂肪动员能力（以pD2表示）显著低于对照者。发现肥胖者pD2的显著降低取决于体重的稳定，而肥胖者的动态pD2阶段值与对照者并无差异。有人提出假说，较低的pD2值可能与体重减轻期间体脂减少幅度较小有关。
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