用于固相肽合成的几种苄基保护基团的酸稳定性。O-苄基酪氨酸重排为3-苄基酪氨酸。 - Suppr

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超能文献

Acid stability of several benzylic protecting groups used in solid-phase peptide synthesis. Rearrangement of O-benzyltyrosine to 3-benzyltyrosine.

作者信息

Erickson B W, Merrifield R B

出版信息

J Am Chem Soc. 1973 May 30;95(11):3750-6. doi: 10.1021/ja00792a046.

DOI:10.1021/ja00792a046

PMID:4708380

Abstract

摘要

相似文献

Acid stability of several benzylic protecting groups used in solid-phase peptide synthesis. Rearrangement of O-benzyltyrosine to 3-benzyltyrosine.用于固相肽合成的几种苄基保护基团的酸稳定性。O-苄基酪氨酸重排为3-苄基酪氨酸。

J Am Chem Soc. 1973 May 30;95(11):3750-6. doi: 10.1021/ja00792a046.

Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N -branching at lysine during solid-phase peptide synthesis.在固相肽合成过程中使用氯代苄氧羰基保护基消除赖氨酸处的N-分支。

J Am Chem Soc. 1973 May 30;95(11):3757-63. doi: 10.1021/ja00792a047.

[Side reactions in peptide synthesis. V. O-sulfonation of serine and threonine during removal of pmc- and mtr-protecting groups from arginine residues in fmoc-solid phase synthesis].[肽合成中的副反应。V. 在芴甲氧羰基-固相合成中从精氨酸残基上去除对甲氧基苄基羰基和间甲苯磺酰基保护基团期间丝氨酸和苏氨酸的O-磺化反应]

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Synthesis of Sulfotyrosine-Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc-Based Solid-Phase Strategy.使用基于Fmoc的固相策略通过掺入氟硫酸化酪氨酸合成含磺基酪氨酸的肽。

Angew Chem Int Ed Engl. 2016 Jan 26;55(5):1835-8. doi: 10.1002/anie.201509016. Epub 2015 Dec 22.

Side reactions in peptide synthesis. VI. A reexamination of the benzyl group in the protection of the side chains of tyrosine and aspartic acid.肽合成中的副反应。VI. 对酪氨酸和天冬氨酸侧链保护中苄基的重新审视。

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Synthesis and biological evaluation of poly-gamma-glutamyl derivatives of methotrexate.甲氨蝶呤聚γ-谷氨酰衍生物的合成及生物学评价

Biochemistry. 1973 Sep 25;12(20):3923-7. doi: 10.1021/bi00744a021.

Solid-phase method for peptide synthesis using macroreticular copolymers.使用大孔网状共聚物进行肽合成的固相方法。

Biochim Biophys Acta. 1971 Jul 20;244(1):201-5. doi: 10.1016/0304-4165(71)90137-1.

Specificity of bacterial collagenase: studies with peptides newly synthesized using the solid-phase method.

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Facile solid-phase synthesis of sulfated tyrosine-containing peptides: Part II. Total synthesis of human big gastrin-II and its C-terminal glycine-extended peptide (G34-Gly sulfate) by the solid-phase segment condensation approach.含硫酸化酪氨酸肽的简便固相合成：第二部分。通过固相片段缩合方法全合成人big胃泌素-II及其C端甘氨酸延伸肽（G34-甘氨酸硫酸盐）。

Chem Pharm Bull (Tokyo). 2001 Aug;49(8):958-63. doi: 10.1248/cpb.49.958.

Increased coupling yields in solid phase peptide synthesis with a modified carbodiimide coupling procedure.采用改良的碳二亚胺偶联方法提高固相肽合成中的偶联产率。

Hoppe Seylers Z Physiol Chem. 1972 Dec;353(12):1973-6.

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