Grosse H
Arch Geschwulstforsch. 1979;49(2):162-7.
Terminal endocarditis develope in cancer patients almost latently. There is no difference between the so-called "tumor-endocarditis" and other verrucous endocarditis associated with terminal tuberculosis, sepsis or rheumatism. It is more frequent in cases with large or ulcerated primary tumours and multiple metastases than in cases with early cancer. It also develope more frequently in well differentiated cancer (squamous and adenocarcinoma) than in indifferentiated forms of cancer. Terminal endocarditis is often seen in patients with cancer of the gallbladder, pancreas, liver, stomach, rectum, and ovary. In carcinoma of the liver, pancreas and biliary tract the trend to embolism is more reduced through icterus than the trend to terminal endocarditis.
终末期心内膜炎在癌症患者中几乎是隐匿性发展的。所谓的“肿瘤性心内膜炎”与其他与终末期肺结核、败血症或风湿热相关的疣状心内膜炎之间并无差异。在有大的或溃疡性原发性肿瘤及多处转移的病例中比早期癌症病例更常见。在高分化癌（鳞状癌和腺癌）中比未分化癌形式更频繁发生。终末期心内膜炎常见于胆囊、胰腺、肝脏、胃、直肠和卵巢癌患者。在肝癌、胰腺癌和胆管癌中，黄疸导致的栓塞倾向比终末期心内膜炎倾向降低得更多。
