6-羟甲基苯并(a)芘作为苯并(a)芘和6-甲基苯并(a)芘的直接致癌物的可能作用。 - Suppr | 超能文献

Possible role of 6-hydroxymethylbenzo(a)pyrene as a proximate carcinogen of benzo(a(pyrene and 6-methylbenzo(a)pyrene.

作者信息

Flesher J W, Sydnor K L

出版信息

Int J Cancer. 1973 Mar 15;11(2):433-7. doi: 10.1002/ijc.2910110221.

DOI:10.1002/ijc.2910110221

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Possible role of 6-hydroxymethylbenzo(a)pyrene as a proximate carcinogen of benzo(a(pyrene and 6-methylbenzo(a)pyrene.6-羟甲基苯并(a)芘作为苯并(a)芘和6-甲基苯并(a)芘的直接致癌物的可能作用。

Int J Cancer. 1973 Mar 15;11(2):433-7. doi: 10.1002/ijc.2910110221.

2

S-Adenosyl-L-methionine is a carbon donor in the conversion of benzo[alpha]pyrene to 6-hydroxymethylbenzo[alpha]pyrene by rat liver S-9.

Cancer Lett. 1982 May-Jun;16(1):91-4. doi: 10.1016/0304-3835(82)90095-7.

3

6-sulfooxymethylbenzo[a]pyrene is an ultimate electrophilic and carcinogenic form of the intermediary metabolite 6-hydroxymethylbenzo[a]pyrene.6-磺氧基甲基苯并[a]芘是中间代谢产物6-羟基甲基苯并[a]芘的一种最终亲电致癌形式。

Biochem Biophys Res Commun. 1997 May 29;234(3):554-8. doi: 10.1006/bbrc.1997.6679.

4

Mutagenic activity of biliary metabolites of 6-hydroxymethylbenzo[a]pyrene.6-羟甲基苯并[a]芘胆汁代谢物的诱变活性。

Mutat Res. 1986 Apr;173(4):251-6. doi: 10.1016/0165-7992(86)90019-9.

5

Association of benzo[a]pyrene with H1 histone in rat-liver nuclei.大鼠肝细胞核中苯并[a]芘与H1组蛋白的关联。

Cancer Lett. 1983 May;19(1):13-20. doi: 10.1016/0304-3835(83)90129-5.

6

Metabolic activation of the carcinogen 6-hydroxymethylbenzo[a]pyrene: formation of an electrophilic sulfuric acid ester and benzylic DNA adducts in rat liver in vivo and in reactions in vitro.致癌物6-羟甲基苯并[a]芘的代谢活化：大鼠肝脏体内及体外反应中亲电子硫酸酯和苄基DNA加合物的形成

Carcinogenesis. 1989 Aug;10(8):1519-28. doi: 10.1093/carcin/10.8.1519.

7

The strong hepatocarcinogenicity of the electrophilic and mutagenic metabolite 6-sulfooxymethylbenzo[a]pyrene and its formation of benzylic DNA adducts in the livers of infant male B6C3F1 mice.亲电和诱变代谢物6-磺氧基甲基苯并[a]芘的强肝癌致癌性及其在雄性幼龄B6C3F1小鼠肝脏中形成苄基DNA加合物的情况。

Biochem Biophys Res Commun. 1990 Oct 15;172(1):85-91. doi: 10.1016/s0006-291x(05)80176-7.

8

The metabolism of benzo[a]pyrene by rat-liver homogenates.大鼠肝脏匀浆对苯并[a]芘的代谢

Biochem Pharmacol. 1967 Apr;16(4):613-8. doi: 10.1016/0006-2952(67)90071-8.

9

Carcinogenicity and metabolic profiles of 6-substituted benzo[a]pyrene derivatives on mouse skin.6-取代苯并[a]芘衍生物对小鼠皮肤的致癌性和代谢谱

Chem Biol Interact. 1978 Jul;22(1):53-67. doi: 10.1016/0009-2797(78)90149-7.

10

Synthesis of putative oxidized metabolites of 8-methylbenzo[a]pyrene.8-甲基苯并[a]芘假定氧化代谢产物的合成。

Carcinogenesis. 1983 Oct;4(10):1297-9. doi: 10.1093/carcin/4.10.1297.

引用本文的文献

1

Carbocations from oxidized metabolites of benzo[a]anthracene: a computational study of their methylated and fluorinated derivatives and guanine adducts.苯并[a]蒽氧化代谢产物产生的碳正离子：对其甲基化和氟化衍生物以及鸟嘌呤加合物的计算研究

Chem Res Toxicol. 2006 Jul;19(7):899-907. doi: 10.1021/tx060067l.

2

Effects of inducers and epoxide hydrase on the metabolism of benzo(a)pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography.诱导剂和环氧化物水解酶对肝脏微粒体及重组系统中苯并(a)芘代谢的影响：高压液相色谱分析

Proc Natl Acad Sci U S A. 1974 Nov;71(11):4356-60. doi: 10.1073/pnas.71.11.4356.

3

Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells.哺乳动物细胞中苯并(a)芘诱变化谢产物的鉴定。

Proc Natl Acad Sci U S A. 1976 Feb;73(2):607-11. doi: 10.1073/pnas.73.2.607.