Anderson J M, Belton N R
J Neurol Neurosurg Psychiatry. 1974 May;37(5):514-20. doi: 10.1136/jnnp.37.5.514.
In a necropsy study of brain water, sodium, and potassium concentrations is newborn infants, abnormalities were found in 10 out of 16 cases who were severely asphyxiated at birth. It is concluded that, although frank cerebral cortical necrosis is not often recognizable in perinatal deaths, early anoxic-ischaemic cerebral damage is frequent after intrapartum asphyxia. Diffuse cerebral swelling was associated with marked electrolyte disturbances and may be regarded as a feature of anoxic-ischaemic encephalopathy in asphyxiated newborn infants.
在一项关于新生儿脑含水量、钠和钾浓度的尸检研究中,16例出生时严重窒息的病例中有10例发现异常。得出的结论是,尽管在围产期死亡中往往无法识别明显的大脑皮质坏死,但产时窒息后早期缺氧缺血性脑损伤很常见。弥漫性脑肿胀与明显的电解质紊乱有关,可被视为窒息新生儿缺氧缺血性脑病的一个特征。