Pallavicini E B, Burgio V L
Minerva Med. 1979 Sep 29;70(42):2897-901.
A 18 years old female patient was admitted to our clinic with a diagnosis of non-Hodgkin malignant lymphoma originating from the subcutaneous tissue of the left paravertebral region. Notwithstanding cycles of polychemotherapy and radiotherapy, clinical conditions rapidly worsened with rapid appearance of an increasing number of cutaneous neoplastic infiltrations. Due to the rapid spread of the malignancy -- as shown by lung X-rays and bone marrow biopsy -- the patient died 8 months after the onset of the disease (2 months after admittance). At autopsy, tumor cell infiltrates were found not only in the bone marrow and lung but also in the liver, adrenals, gonads and spinal cord. Histological and cytochemical features -- both in bioptic and autopic tissue specimens -- were quite similar to those of Ewing's sarcoma of bone. On the whole, of these clinical and histopathological features, this can be considered a case of "extraskeletal Ewing's sarcoma" as described by Angervall and Enzinger and recently by E. H. Soule et Al.
一名18岁女性患者因诊断为起源于左椎旁区域皮下组织的非霍奇金恶性淋巴瘤入住我院。尽管进行了多轮化疗和放疗，但临床状况迅速恶化，皮肤肿瘤浸润数量迅速增加。由于恶性肿瘤的快速扩散——如肺部X光片和骨髓活检所示——患者在疾病发作后8个月（入院后2个月）死亡。尸检发现，肿瘤细胞浸润不仅存在于骨髓和肺部，还存在于肝脏、肾上腺、性腺和脊髓。活检和尸检组织标本中的组织学和细胞化学特征与骨尤因肉瘤非常相似。总体而言，综合这些临床和组织病理学特征，这可被视为Angervall和Enzinger以及最近E. H. Soule等人所描述的“骨外尤因肉瘤”病例。
