Coma-Canella I, Lopez-Sendon J, Gamallo C
Am Heart J. 1979 Nov;98(5):613-20. doi: 10.1016/0002-8703(79)90287-4.
In this paper we describe clinical and hemodynamic data in ten patients with right ventricular infarction and low output syndrome. Atrioventricular block and supraventricular arrhythmias were a common finding. All of them had a right atrial pressure disproportionately increased (average 16.3 +/- 5.2 mm. Hg) in relation to left ventricular filling pressure (average 15 +/- 4.5 mm. Hg), and a very low cardiac index (average 1.42 +/- 0.45 liters/min./m.2). The right atrial pulse tracings were similar to those of constrictive pericarditis, showing a deep "y" descent in every patient. We made the differential diagnosis between similar hemodynamic entities and constructed function curves of right and left ventricles. Right ventricular diastolic work index was always increased (average 6.26 +/- 3.63 gm./beat/M.2), being higher than net work index (average 3.28 +/- 1.87 gm./beat/M.2). While all function curves of the right ventricle were flat or depressed, those of the left ventricle were very different. Treatment consisted mainly of fluid overload and, in some cases, of vasodilators or dopamine. Mortality rate was 40%. We think that coexisting left ventricular damage may account in part for the bad prognosis of these patients.
在本文中,我们描述了10例右心室梗死合并低输出量综合征患者的临床和血流动力学数据。房室传导阻滞和室上性心律失常是常见表现。所有患者右心房压力相对于左心室充盈压均不成比例地升高(平均16.3±5.2毫米汞柱),而左心室充盈压平均为15±4.5毫米汞柱,且心脏指数极低(平均1.42±0.45升/分钟/平方米)。右心房脉搏描记图与缩窄性心包炎患者相似,每位患者均显示出深的“y”降支。我们对相似的血流动力学情况进行了鉴别诊断,并绘制了左右心室的功能曲线。右心室舒张作功指数总是升高(平均6.26±3.63克/搏/平方米),高于净作功指数(平均3.28±1.87克/搏/平方米)。虽然右心室的所有功能曲线均平坦或降低,但左心室的功能曲线却大不相同。治疗主要包括液体超负荷,在某些情况下还包括使用血管扩张剂或多巴胺。死亡率为40%。我们认为并存的左心室损害可能部分解释了这些患者的不良预后。