Toivanen P, Hirvonen T
Clin Exp Immunol. 1970 Oct;7(4):533-9.
Foeto-maternal ABO incompatibility is associated with increased placental weight; the observation, however, was valid only in the male placentas of primigravidas. It is suggested that a cumulative effect of two incompatibilities, Y chromosome-dependent incompatibility and ABO incompatibility, is needed for this influence on placental weight to be manifested, since male placentas were heavier than female placentas in ABO incompatible cases but not in ABO compatible cases. Also, this effect was found only in the first pregnancy. It is concluded that in later pregnancies the effect of multiparity masks the influence of ABO incompatibility and foetal sex. Different foeto-maternal Rh combinations were not found to have any effect on placental weight.
母婴ABO血型不合与胎盘重量增加有关;然而,这一观察结果仅在初产妇的男性胎盘中有效。有人认为,要表现出对胎盘重量的这种影响,需要Y染色体依赖性不相容性和ABO不相容性这两种不相容性的累积效应,因为在ABO血型不相容的情况下,男性胎盘比女性胎盘重,但在ABO血型相容的情况下并非如此。此外,这种效应仅在首次怀孕时发现。得出的结论是,在后续妊娠中,多胎妊娠的影响掩盖了ABO血型不相容性和胎儿性别的影响。未发现不同的母婴Rh组合对胎盘重量有任何影响。