肾移植受者中马抗淋巴细胞球蛋白的静脉给药及循环中抗马球蛋白抗体的检测
The intravenous administration of equine antilymphocytic globulin in renal transplant recipients and the detection of circulating antibodies to equine globulin.
作者信息
James K, Pullar D M, Morton J B, Dalton R G, Nolan B, Woodruff M F
出版信息
Clin Exp Immunol. 1971 Apr;8(4):529-42.
Abstract
Methods are described for the intravenous administration of equine antilymphocytic globulin (ALG) to renal transplant recipients. The development of circulating antibodies to the equine IgG has been investigated using primary and secondary immunological procedures. The need for primary immunoassay procedures to assess both the immune response and induction of tolerance to equine IgG in ALG treated patients is extensively discussed.
摘要
本文描述了给肾移植受者静脉注射马抗淋巴细胞球蛋白（ALG）的方法。已使用一级和二级免疫程序研究了针对马IgG的循环抗体的产生。文中广泛讨论了使用一级免疫测定程序来评估ALG治疗患者对马IgG的免疫反应和耐受性诱导的必要性。
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