新生犬血糖与肝脏葡萄糖生成之间的关系。
Relations between blood glucose and hepatic glucose production in newborn dogs.
作者信息
Hetenyi G, Varma S, Cowan J S
出版信息
Br Med J. 1972 Jun 10;2(5814):625-7. doi: 10.1136/bmj.2.5814.625.
Abstract
No correlation was found between the concentration of glucose in blood plasma and the rate of hepatic glucose production in newborn pups aged 2(1/2)-112 hours. During the first few hours of life the hypoglycaemic response to insulin was small or absent. Later the response seemed exaggerated mainly owing to a slow recovery to normoglycaemia. This latter observation can be entirely accounted for by the lack of a feedback mechanism between the plasma concentration and the hepatic rate of production of glucose.
摘要
在出生2（1/2）至112小时的新生幼崽中，未发现血浆葡萄糖浓度与肝脏葡萄糖生成速率之间存在相关性。在出生后的最初几个小时内，对胰岛素的低血糖反应很小或不存在。后来，这种反应似乎被夸大了，主要是由于恢复到正常血糖水平的速度较慢。后一种观察结果完全可以通过血浆浓度与肝脏葡萄糖生成速率之间缺乏反馈机制来解释。
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Recent Prog Horm Res. 1963;19:445-88.
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Lancet. 1963 Jan 26;1(7274):200. doi: 10.1016/s0140-6736(63)91215-7.
3
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