Somerville J, Ross D, Ross J K
Thorax. 1972 Sep;27(5):583-5. doi: 10.1136/thx.27.5.583.
The fate is described of 11 patients who had a stored pulmonary valve homograft mounted on a frame or in a Dacron jacket used for mitral valve replacement. Mitral regurgitation due to holes in the attenuated cusps occurred in nine by one year, requiring re-operation or causing death. Only one patient remains well with moderate mitral regurgitation after two years. Since January 1967, 118 patients have had mitral valve replacement with a preserved cadaver semilunar homograft valve mounted in a jacket or frame (Murray, Roschlau, and Lougheed, 1956; Heimbecker , 1962). In all except 11 patients the aortic valve was used. However, in the 11 patients in whom an inverted pulmonary valve was used (Lower, Stofer, and Shumway, 1961) the clinical course has been different. The purpose of this report is to draw attention to the problems and discourage the use of this form of mitral valve replacement.
本文描述了11例患者的情况，这些患者接受了安装在框架上或置于涤纶外套中的储存肺动脉瓣同种异体移植瓣膜用于二尖瓣置换术。因瓣叶变薄出现孔洞导致二尖瓣反流，9例患者在1年内出现这种情况，需要再次手术或导致死亡。两年后只有1例患者存在中度二尖瓣反流且情况良好。自1967年1月以来，118例患者接受了安装在涤纶外套或框架中的保存尸体半月瓣同种异体移植瓣膜进行二尖瓣置换术（默里、罗斯克劳和卢格希德，1956年；海姆贝克，1962年）。除11例患者外，其余均使用主动脉瓣。然而，在11例使用倒置肺动脉瓣的患者中（洛厄、斯托弗和舒姆韦，1961年），临床过程有所不同。本报告的目的是提醒注意这些问题，并不鼓励使用这种形式的二尖瓣置换术。
