Zybina E V
Tsitologiia. 1979 Nov;21(11):1253-8.
Folding pattern of the nucleus envelope and intranuclear membrane structures in trophoblast giant cells and in trophoblast of the intermediate region of the rat placenta have been studied. Cells of the intermediate region of the placenta demonstrate deep invaginations resulting in the appearance of lobulated nuclei. Invaginations of the nuclear envelope pass on a narrow fold made by an inner nuclear membrane. The polyploid nuclei of trophoblast giant cells have superficial folds and deeper finger-like invaginations in their envelopes. Such folding trophoblast nuclei in two populations examined are met throughout the whole ontogenesis of the cell. In the giant cells, individual intranuclear tubes or their accumulations are seen. The tubes are made by a unit membrane and are surrounded with a matrix. The nuclear chromatin, diffuse or condenced, is in association with the tube surface. The tubes are met near the nucleolus and on its surface, where these are surrounded with the granular component of the nucleolus. In the trophoblast of the intermediate region of the placenta, intranuclear concentric membranes have been found; made of paired membranes, intramembranous space being filled with electron dense matrix. The concentric membranes lie separately in the karyoplasm, not being associated with the chromatin.
对大鼠胎盘滋养层巨细胞和中间区域滋养层细胞核膜的折叠模式及核内膜结构进行了研究。胎盘中间区域的细胞呈现出深深的内陷，导致出现分叶状细胞核。核膜的内陷通过内核膜形成的狭窄褶皱传递。滋养层巨细胞的多倍体细胞核在其包膜上有表面褶皱和更深的指状内陷。在所研究的两个细胞群体中，这种折叠的滋养层细胞核在细胞的整个个体发育过程中都能见到。在巨细胞中，可以看到单个的核内管或它们的聚集物。这些管由单位膜构成，并被基质包围。核染色质，呈弥散或浓缩状态，与管表面相关联。这些管在核仁附近及其表面可见，在那里它们被核仁的颗粒成分包围。在胎盘中间区域的滋养层中，发现了核内同心膜；由成对的膜构成，膜间空间充满电子致密基质。同心膜单独位于核质中，与染色质不相关联。
