在回避训练期间对边缘系统生化变化的放射自显影显示。
Autoradiographic demonstration of biochemical changes in the limbic system during avoidance training.
作者信息
Beach G, Emmens M, Kimble D P, Lickey M
出版信息
Proc Natl Acad Sci U S A. 1969 Mar;62(3):692-6. doi: 10.1073/pnas.62.3.692.
Abstract
After injection of leucine-H(3), members from eight triplets of rats were assigned to one of three treatment groups: avoidance learning, the same handling and shocks without opportunity to learn, or passive control. Autoradiographic grains over all nuclei were counted "blind." In the hippocampus, the number of grains for the learning rats was reliably greater than that for either control. The differences approached statistical significance in the entorhinal cortex and the septal area but not in other brain areas or in the liver. Although the processes responsible for the increased incorporation are not yet defined, these changes probably are the result of learning rather than of stress.
摘要
注射亮氨酸 - H(3) 后，将八组三联体大鼠中的成员分配到三个治疗组之一：回避学习组、接受相同处理和电击但无学习机会组或被动对照组。对所有细胞核上的放射自显影颗粒进行“盲法”计数。在海马体中，学习组大鼠的颗粒数量确实比两个对照组都多。在内嗅皮质和隔区，差异接近统计学意义，但在其他脑区或肝脏中则不然。尽管导致掺入增加的过程尚未明确，但这些变化可能是学习的结果而非应激的结果。
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