Treharne R W, Brighton C T, Korostoff E, Pollack S R
Clin Orthop Relat Res. 1979 Nov-Dec(145):300-6.
Although many investigators have electrically stimulated osteogenesis in vivo, this phenomenon has not been reported in vitro. In this work direct and pulsating currents were applied to in vitro fetal rat tibiae. The results indicated that electric current did cause osteogenesis in vitro, precipitates of calcium compounds formed in the cathode region, and direct current was more effective in stimulating bone growth than pulsed current delivering the same total charge (coulombs).
尽管许多研究人员已在体内通过电刺激诱导成骨,但这种现象在体外尚未见报道。在本研究中,将直流电和脉动电流施加于体外培养的胎鼠胫骨。结果表明,电流确实能在体外诱导成骨,在阴极区域形成了钙化合物沉淀,并且在输送相同总电荷量(库仑)时,直流电比脉动电流在刺激骨生长方面更有效。