Young J P
Genetics. 1979 Jul;92(3):971-82. doi: 10.1093/genetics/92.3.971.
Cyclical parthenogenesis exaggerates the force of selection relative to recombination and will therefore enhance interlocus effects. Observations of electrophoretic variation in a natural population of Daphnia magna Straus (Crustacea: Cladocera) are interpreted in this light. Sexual reproduction led to Hardy-Weinberg equilibrium, but heterozygote excesses rapidly developed at each of three observed loci during subsequent parthenogenesis. Homozygote fecundity was often lower than that of heterozygotes; this may have been the cause of some of the observed frequency changes. The superior fitness of the enzyme heterozygotes does not imply that selection was necessarily acting on the enzyme loci thermselves, since apparent heterosis is the expected result of linkage disequilibrium.
周期性孤雌生殖相对于重组夸大了选择的力量，因此会增强基因座间效应。基于此观点对大型溞（甲壳纲：枝角亚目）自然种群的电泳变异观察结果进行了解释。有性生殖导致哈迪-温伯格平衡，但在随后的孤雌生殖过程中，在观察到的三个基因座中的每一个上都迅速出现了杂合子过剩现象。纯合子的繁殖力往往低于杂合子；这可能是观察到的一些频率变化的原因。酶杂合子的适应性优势并不意味着选择必然作用于酶基因座本身，因为明显的杂种优势是连锁不平衡的预期结果。
