Gindhart T D, Tucker W Y, Choy S H
Am J Surg Pathol. 1979 Aug;3(4):353-61. doi: 10.1097/00000478-197908000-00006.
An unusual case of cavernous hemangioma of the superior mediastinum in a 38-year-old male is presented. Mediastinal hemangiomas occur more often in children and are usually localized in the anterior-superior compartment in all age groups. Slow expansile growth, lack of infiltration of adjacent structures and microscopically mature cellular elements clearly marked the benign nature of the lesion. Vascular mesenchymal tumors in this location must be approached with caution because of the risks of hemorrhage or local infiltration of vital structures. Electron microscopy revealed active endothelial cells, smooth muscle cells, and intercellular matrix components suggestive of smooth muscle cell origin. Computerized tomography delineated the lesion clearly and demonstrated identical densities for the mass and adjacent blood vessels.
本文报告了一例38岁男性罕见的上纵隔海绵状血管瘤病例。纵隔血管瘤在儿童中更为常见,在所有年龄组中通常位于前上纵隔。缓慢的膨胀性生长、不侵犯相邻结构以及显微镜下成熟的细胞成分明确表明该病变为良性。由于存在出血或重要结构局部浸润的风险,对此部位的血管间叶肿瘤必须谨慎处理。电子显微镜检查显示有活跃的内皮细胞、平滑肌细胞以及提示平滑肌细胞起源的细胞间基质成分。计算机断层扫描清晰地勾勒出病变,并显示肿块与相邻血管密度相同。