Thornton J R, Lohni M D
Equine Vet J. 1979 Oct;11(4):235-8. doi: 10.1111/j.2042-3306.1979.tb01354.x.
Lactic dehydrogenase, although widely distributed in most tissues, was more highly concentrated in skeletal muscle, cardiac muscle, kidney and liver. Isoenzyme patterns showed a selective concentration of LDH5 in skeletal muscle while in the heart LDH 1 and 2 were predominant. In contrast, creatine kinase was only present in substantial concentration in skeletal and cardiac muscle. The serum concentrationof both enzymes showed a wide range of activity.
乳酸脱氢酶虽然广泛分布于大多数组织中,但在骨骼肌、心肌、肾脏和肝脏中的浓度更高。同工酶模式显示,LDH5在骨骼肌中选择性富集,而在心脏中LDH1和LDH2占主导地位。相比之下,肌酸激酶仅在骨骼肌和心肌中大量存在。这两种酶的血清浓度显示出广泛的活性范围。