Gnehm H E, Bernasconi S, Zachmann M
Helv Paediatr Acta. 1979;34(6):529-35.
5 patients are presented in whom cerebral trauma of varying intensity during childhood was followed by pituitary insufficiency. There was no correlation between the severity of injury and subsequent hormonal defects. Among other anterior pituitary hormone defects, growth retardation secondary to growth hormone deficiency is a predominant feature in the pediatric age group. Only one patient requires treatment of neurohormonal diabetes insipidus. The prevalence of traumatic origin among the hypopituitary dwarfs observed in our departement is 3.7%.
本文报告5例儿童期不同程度脑外伤后发生垂体功能减退的病例。损伤严重程度与随后的激素缺陷之间无相关性。在其他垂体前叶激素缺陷中,生长激素缺乏继发的生长发育迟缓是儿童年龄组的主要特征。仅1例患者需要治疗神经源性尿崩症。在我们科室观察到的垂体功能减退性侏儒症中,创伤性病因的患病率为3.7%。