膜电容的研究。I. 由滤纸和脂质类似物组成的模型膜。
Studies of electric capacitance of membranes. I. A model membrane composed of a filter paper and a lipid analogue.
作者信息
Kobatake Y, Irimajiri A, Matsumoto N
出版信息
Biophys J. 1970 Aug;10(8):728-44. doi: 10.1016/S0006-3495(70)86332-9.
A hydrophobic filter paper of a given pore size containing a synthetic lipid, i.e. dioleyl phosphate, was interposed between aqueous electrolyte solutions having the same chemical composition and temperature. The electric capacitance and conductance of the membrane immersed in various concentrations of KCl were measured in the frequency range from 20 to 3 x 10(6) cycle/sec. The observed capacitance and conductance were found to be strongly dependent on the applied frequency. A theory is proposed to account for this dispersion of impedance observed in the present membrane-electrolyte system. The dispersion is attributed to the formation of bilayer membranes of the lipid inside the filter paper. The effects of the salt concentration, the adsorbed quantity of the lipid, and the pore size of the filter paper on the capacitance and conductance of the membrane are discussed in terms of the distribution function of bilayers formed within the filter paper.
将含有合成脂质（即磷酸二油酰酯）的特定孔径疏水滤纸置于具有相同化学成分和温度的水电解质溶液之间。在20至3×10⁶ 周期/秒的频率范围内，测量了浸入不同浓度KCl中的该膜的电容和电导。观察到的电容和电导强烈依赖于所施加的频率。提出了一种理论来解释在当前膜 - 电解质系统中观察到的这种阻抗色散现象。这种色散归因于滤纸内部脂质双层膜的形成。根据滤纸内形成的双层膜的分布函数，讨论了盐浓度、脂质吸附量和滤纸孔径对膜电容和电导的影响。
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