大鼠肾盂肾炎治疗：与尿液中排泄的抗菌活性随机相关。
Pyelonephritis therapy in rats: random association with excreted urinary antibacterial activity.
作者信息
Burrous S E, Freedman R, Chamberlain R E, Basson R P
出版信息
Appl Microbiol. 1970 Oct;20(4):598-9. doi: 10.1128/am.20.4.598-599.1970.
Abstract
In vitro activities or excreted urinary activities of 56 generic and experimental drugs against two organisms commonly associated with human pyelonephritis, Escherichia coli and Proteus mirabilis, are not correlated with the in vivo activities of these compounds as measured by reduction of viable organisms in kidneys in experimental pyelonephritis.
摘要
56种通用药物和实验药物针对两种通常与人类肾盂肾炎相关的生物体——大肠杆菌和奇异变形杆菌的体外活性或排泄尿液活性，与这些化合物在实验性肾盂肾炎中通过肾脏中活菌数量减少所测得的体内活性不相关。
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Appl Microbiol. 1970 Oct;20(4):598-9. doi: 10.1128/am.20.4.598-599.1970.
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本文引用的文献
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ANTIMICROBIAL SUSCEPTIBILITY OF PATHOGENIC ORGANISMS ISOLATED FROM THE URINARY TRACT IN 1963.1963年从泌尿道分离出的致病微生物的药敏情况
N Y State J Med. 1965 Mar 1;65:649-52.
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The treatment of urinary tract infections with a new antibiotic-cephaloglycin.用一种新型抗生素——头孢甘氨酸治疗尿路感染。
J Urol. 1969 Mar;101(3):392-5. doi: 10.1016/s0022-5347(17)62352-8.
3
Rat pyelonephritis model suitable for primary or secondary screening.适用于初次或二次筛选的大鼠肾盂肾炎模型。
Appl Microbiol. 1969 Sep;18(3):448-51. doi: 10.1128/am.18.3.448-451.1969.
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