鼠伤寒沙门氏菌鞭毛蛋白的甲基化作用。
Methylation of the flagellin of Salmonella typhimurium.
作者信息
Tronick S R, Martinez R J
出版信息
J Bacteriol. 1971 Jan;105(1):211-9. doi: 10.1128/jb.105.1.211-219.1971.
Abstract
The methylation of endogenous proteins by Salmonella typhimurium SL 870 was investigated in cell-free extracts by using S-adenosylmethionine as methyl donor. Several lines of evidence are presented which suggest that one of the methylated products is the protein flagellin. Mutant strains of SL 870 (nml(-)fla(+) and nml(+)fla(-)) were also found to synthesize epsilon-N-methyl-lysine. It is proposed that S. typhimurium possesses at least two genes specifying different methylating enzymes. One gene product is a flagellin-specific methylating enzyme, whereas the other gene(s) codes for enzymes that methylate one or more other cell proteins.
摘要
利用S-腺苷甲硫氨酸作为甲基供体，在无细胞提取物中研究了鼠伤寒沙门氏菌SL 870对内源蛋白质的甲基化作用。提供了几条证据表明甲基化产物之一是蛋白质鞭毛蛋白。还发现SL 870的突变株（nml(-)fla(+)和nml(+)fla(-)）能合成ε-N-甲基赖氨酸。有人提出，鼠伤寒沙门氏菌至少拥有两个指定不同甲基化酶的基因。一种基因产物是鞭毛蛋白特异性甲基化酶，而另一个基因编码使一种或多种其他细胞蛋白质甲基化的酶。
相似文献
1
Methylation of the flagellin of Salmonella typhimurium.鼠伤寒沙门氏菌鞭毛蛋白的甲基化作用。
J Bacteriol. 1971 Jan;105(1):211-9. doi: 10.1128/jb.105.1.211-219.1971.
2
Integration, at hag or elsewhere, of H2 (phase-2 flagellin) genes transduced from Salmonella to Escherichia coli.从沙门氏菌转导至大肠杆菌的H2（第二阶段鞭毛蛋白）基因在哈格或其他地方的整合。
Genetics. 1975 Dec;81(4):595-614. doi: 10.1093/genetics/81.4.595.
3
Effect of proteolytic enzymes on bacterial flagella.蛋白水解酶对细菌鞭毛的作用。
J Bacteriol. 1972 Mar;109(3):1239-46. doi: 10.1128/jb.109.3.1239-1246.1972.
4
Heterogeneity of the stability of messenger ribonucleic acid in Salmonella typhimurium.鼠伤寒沙门氏菌中信使核糖核酸稳定性的异质性
J Bacteriol. 1967 Jan;93(1):115-21. doi: 10.1128/jb.93.1.115-121.1967.
5
Defective ribosomes in chloramphenicol-treated Escherichia coli.氯霉素处理的大肠杆菌中的核糖体缺陷
J Mol Biol. 1971 May 14;57(3):457-73. doi: 10.1016/0022-2836(71)90103-3.
6
The enzymatic alpha-N-methylation of histidine.组氨酸的酶促α-N-甲基化作用。
J Biol Chem. 1970 Nov 25;245(22):5967-73.
7
The attenuated phenotype of a Salmonella typhimurium flgM mutant is related to expression of FliC flagellin.鼠伤寒沙门氏菌flgM突变体的减毒表型与鞭毛蛋白FliC的表达有关。
J Bacteriol. 1996 May;178(10):2911-5. doi: 10.1128/jb.178.10.2911-2915.1996.
8
Absence of messenger ribonucleic acid specific for flagellin in non-flagellate mutants of Salmonella.沙门氏菌无鞭毛突变体中不存在鞭毛蛋白特异性信使核糖核酸。
J Mol Biol. 1975 Jul 15;95(4):549-56. doi: 10.1016/0022-2836(75)90316-2.
9
Oral immunization with live, avirulent fla+ strains of Salmonella protects mice against subsequent oral challenge with Salmonella typhimurium.
J Infect Dis. 1988 Jan;157(1):78-84. doi: 10.1093/infdis/157.1.78.
10
In vitro methylation of bacterial chemotaxis proteins: characterization of protein methyltransferase activity in crude extracts of Salmonella typhimurium.细菌趋化蛋白的体外甲基化：鼠伤寒沙门氏菌粗提物中蛋白质甲基转移酶活性的表征
J Supramol Struct. 1980;13(3):315-28. doi: 10.1002/jss.400130305.
引用本文的文献
1
Flagellin lysine methyltransferase FliB catalyzes a [4Fe-4S] mediated methyl transfer reaction.鞭毛蛋白赖氨酸甲基转移酶 FliB 催化一个 [4Fe-4S] 介导的甲基转移反应。
PLoS Pathog. 2021 Nov 17;17(11):e1010052. doi: 10.1371/journal.ppat.1010052. eCollection 2021 Nov.
2
Arming the troops: Post-translational modification of extracellular bacterial proteins.武装部队：胞外细菌蛋白的翻译后修饰。
Sci Prog. 2020 Oct-Dec;103(4):36850420964317. doi: 10.1177/0036850420964317.
3
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.沙门氏菌鞭毛甲基化促进细菌黏附和宿主细胞入侵。
Nat Commun. 2020 Apr 24;11(1):2013. doi: 10.1038/s41467-020-15738-3.
4
Bacterial flagella: twist and stick, or dodge across the kingdoms.细菌鞭毛：扭转并附着，还是在不同界间穿梭躲避。
PLoS Pathog. 2015 Jan 15;11(1):e1004483. doi: 10.1371/journal.ppat.1004483. eCollection 2015 Jan.
5
Posttranslational modification of flagellin FlaB in Shewanella oneidensis.希瓦氏菌 FlaB 鞭毛蛋白的翻译后修饰。
J Bacteriol. 2013 Jun;195(11):2550-61. doi: 10.1128/JB.00015-13. Epub 2013 Mar 29.
6
The LysR-type transcriptional regulator LeuO controls expression of several genes in Salmonella enterica serovar Typhi.LysR 型转录调节因子 LeuO 控制伤寒沙门氏菌中多个基因的表达。
J Bacteriol. 2008 Mar;190(5):1658-70. doi: 10.1128/JB.01649-07. Epub 2007 Dec 21.
7
Whole proteome analysis of post-translational modifications: applications of mass-spectrometry for proteogenomic annotation.翻译后修饰的全蛋白质组分析：质谱技术在蛋白质基因组注释中的应用
Genome Res. 2007 Sep;17(9):1362-77. doi: 10.1101/gr.6427907. Epub 2007 Aug 9.
8
Mycobacterial heparin-binding hemagglutinin and laminin-binding protein share antigenic methyllysines that confer resistance to proteolysis.分枝杆菌肝素结合血凝素和层粘连蛋白结合蛋白共享赋予抗蛋白酶解能力的抗原性甲基赖氨酸。
Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10759-64. doi: 10.1073/pnas.162246899. Epub 2002 Jul 29.
9
Flagellar filament structure and cell motility of Salmonella typhimurium mutants lacking part of the outer domain of flagellin.缺失鞭毛蛋白部分外部结构域的鼠伤寒沙门氏菌突变体的鞭毛丝结构和细胞运动性
J Bacteriol. 1995 Feb;177(4):1090-3. doi: 10.1128/jb.177.4.1090-1093.1995.
10
A comparative structural analysis of the flagellin monomers of Caulobacter crescentus indicates that these proteins are encoded by two genes.新月柄杆菌鞭毛蛋白单体的比较结构分析表明，这些蛋白质由两个基因编码。
J Bacteriol. 1982 May;150(2):925-33. doi: 10.1128/jb.150.2.925-933.1982.
本文引用的文献
1
The Biology of Isolated Chromatin: Chromosomes, biologically active in the test tube, provide a powerful tool for the study of gene action.孤立染色质的生物学：在试管中具有生物活性的染色体为研究基因作用提供了一个有力的工具。
Science. 1968 Jan 5;159(3810):47-56. doi: 10.1126/science.159.3810.47.
2
HOST SPECIFICITY OF DNA PRODUCED BY ESCHERICHIA COLI V . THE ROLE OF METHIONINE IN THE PRODUCTION OF HOST SPECIFICITY.大肠杆菌产生的DNA的宿主特异性V. 甲硫氨酸在宿主特异性产生中的作用
J Mol Biol. 1965 Feb;11:247-56. doi: 10.1016/s0022-2836(65)80055-9.
3
IMMUNOGENICITY OF ANTIGEN-CONTAINING RIBONUCLEIC ACID PREPARATIONS FROM MACROPHAGES.来自巨噬细胞的含抗原核糖核酸制剂的免疫原性
Nature. 1965 Jan 30;205:470-4. doi: 10.1038/205470a0.
4
RECONSTITUTION OF BACTERIAL FLAGELLA IN VITRO.体外细菌鞭毛的重组
J Mol Biol. 1964 Oct;10:42-56. doi: 10.1016/s0022-2836(64)80026-7.
5
IN VITRO FORMATION OF FLAGELLA-LIKE FILAMENTS AND OTHER STRUCTURES FROM FLAGELLIN.鞭毛蛋白在体外形成类鞭毛丝及其他结构
J Mol Biol. 1964 Jul;9:168-85. doi: 10.1016/s0022-2836(64)80098-x.
6
THE OCCURRENCE OF EPSILON-N-METHYL LYSINE IN HISTONES.组蛋白中ε-N-甲基赖氨酸的存在情况。
Biochemistry. 1964 Jan;3:10-5. doi: 10.1021/bi00889a003.
7
A METHOD FOR THE PURIFICATION OF BACTERIAL FLAGELLA BY ION EXCHANGE CHROMATOGRAPHY.一种通过离子交换色谱法纯化细菌鞭毛的方法。
J Gen Microbiol. 1963 Oct;33:115-20. doi: 10.1099/00221287-33-1-115.
8
Determination of ornithine, lysine, arginine, citrulline and histidine.鸟氨酸、赖氨酸、精氨酸、瓜氨酸和组氨酸的测定。
J Chromatogr. 1963 Mar;10:404-7. doi: 10.1016/s0021-9673(01)92328-3.
9
Epsilon-N-Methyl-lysine in bacterial flagellar protein.细菌鞭毛蛋白中的ε-N-甲基赖氨酸
Nature. 1959 Jul 4;184:56-7. doi: 10.1038/184056b0.
10
Antigen-antibody reactions in gels. IV. Types of reactions in coordinated systems of diffusion.凝胶中的抗原-抗体反应。IV. 扩散协调系统中的反应类型。
Acta Pathol Microbiol Scand. 1953;32(2):230-40.
Zotero 插件