印度儿童肝硬化中的溶血性贫血
Haemolytic anaemia in Indian childhood cirrhosis.
作者信息
Perkash A, Nair A, Bhorchi R, Walia B N
出版信息
Arch Dis Child. 1971 Feb;46(245):46-50. doi: 10.1136/adc.46.245.46.
Fifty-five patients with Indian childhood cirrhosis were investigated for the occurrence of haemolysis and for its possible underlying mechanisms. Increased haemolysis was present in 76% of patients, and was severe in 12%. The degree of anaemia was not always proportional to the severity of haemolysis. No single factor accounted for haemolysis. Evidence of hypersplenism was present in only 7 (13%) patients. The haemolysis appeared to be more severe in patients with advanced liver disease. Evidence for autoimmune haemolytic anaemia was found in 27% of patients. No relation was seen between the degree of haemolysis and hypercholesterolaemia. These findings are compared with those reported in adult patients with cirrhosis of the liver.
对55例印度儿童肝硬化患者进行了溶血发生情况及其潜在机制的调查。76%的患者存在溶血增加，其中12%的患者溶血严重。贫血程度并不总是与溶血严重程度成正比。没有单一因素可解释溶血现象。仅7例（13%）患者有脾功能亢进的证据。晚期肝病患者的溶血似乎更严重。27%的患者发现自身免疫性溶血性贫血的证据。未发现溶血程度与高胆固醇血症之间存在关联。将这些发现与成年肝硬化患者的报告结果进行了比较。
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