发情周期对催产素在体内对大鼠卵巢收缩性作用的影响。

Influence of the estrous cycle on the action of oxytocin on rat ovarian contractility in vivo.

作者信息

Roca R A, Garófalo E G, Píriz H, Martino I, Rieppi G

出版信息

Fertil Steril. 1977 Feb;28(2):205-8. doi: 10.1016/s0015-0282(16)42384-8.

Abstract

This investigation was designed to determine the influence of the estrous cycle on the response of ovarian smooth muscle to oxytocin. Muscular activity in vivo was studied by recording intraovarian pressure. Intra-aortic injections of oxytocin were given to the rats at all stages of the estrous cycle. The effect of oxytocin was evaluated by the number of responding ovaries and the magnitude of the responses. According to these parameters, a greater response was observed during proestrus, compared with the other cycle stages. The significance of these results id discussed.

摘要

本研究旨在确定发情周期对卵巢平滑肌对催产素反应的影响。通过记录卵巢内压力来研究体内肌肉活动。在发情周期的所有阶段，对大鼠进行主动脉内注射催产素。通过有反应的卵巢数量和反应强度来评估催产素的作用。根据这些参数，与其他周期阶段相比，在发情前期观察到更大的反应。讨论了这些结果的意义。