草酸盐中毒时的血浆草酸和钙水平。
Plasma oxalic acid and calcium levels in oxalate poisoning.
作者信息
Zarembski P M, Hodgkinson A
出版信息
J Clin Pathol. 1967 May;20(3):283-5. doi: 10.1136/jcp.20.3.283.
Observations are reported on five cases of suicide or attempted suicide by poisoning with oxalic acid or ethylene glycol. Elevated oxalic acid levels were observed in the plasma, stomach contents, and a number of tissues. Raised oxalic acid levels in plasma were associated with reduced total and ultrafilterable calcium levels. It is suggested that the reduction in plasma total calcium level is due mainly to the deposition of calcium oxalate in the soft tissues, but inhibition of the parathyroid glands may be a contributory factor. Microscopic examination of various tissues indicated that oxalic acid is deposited in the tissues in two forms: (1) crystalline calcium oxalate dihydrate in the kidney and (2) a non-crystalline complex of calcium oxalate and lipid in liver and other tissues.
报告了5例因草酸或乙二醇中毒导致自杀或自杀未遂的病例观察结果。在血浆、胃内容物和一些组织中观察到草酸水平升高。血浆中草酸水平升高与总钙和可超滤钙水平降低有关。提示血浆总钙水平降低主要是由于草酸钙在软组织中沉积，但甲状旁腺受抑制可能是一个促成因素。对各种组织的显微镜检查表明，草酸以两种形式沉积在组织中：（1）肾中的二水合草酸钙晶体；（2）肝脏和其他组织中的草酸钙与脂质的非晶体复合物。
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