Harms D
Klin Padiatr. 1978 Mar;190(2):196-202.
Increasing sclerosis in the thoracolumbar spine has been followed up in a boy suffering from tuberous sclerosis. The earlist abnormality appearing as an irregular density in the radix of the posterior arch of the first lumbar vertebra has been detected at the age of one year. Until the ninth year of life the disease process has involved the vertebral column from T-8 to L-2. During the course roentgenograms revealed several diffuse areas of opacification with ill-defined outlines which tended to merge. As a rule all vertebrae were affected asymmetrically. Neither deformities of the vertebrae nor functional impairment of the axial skeleton have been found. Based on X ray appearance classification of characteristic and accessory bone abnormalities in tuberous sclerosis was discussed.
对一名患有结节性硬化症的男孩进行了胸腰椎硬化进展情况的随访。最早在1岁时就检测到异常,表现为第一腰椎后弓根部不规则密度影。直到9岁,疾病进程已累及从T-8到L-2的脊柱。在此期间,X线片显示出几个边界不清的弥漫性致密区,这些致密区有融合趋势。通常所有椎体均不对称受累。未发现椎体畸形或轴向骨骼功能损害。基于X线表现,讨论了结节性硬化症特征性和附属骨异常的分类。