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不同剂量泼尼松龙治疗儿童免疫性血小板减少症的疗效

The effect of different doses of prednisolone in the treatment of childhood ITP.

作者信息

Hathirat P, Isarangkura P, Uthai K

出版信息

Southeast Asian J Trop Med Public Health. 1979 Sep;10(3):373-84.

PMID:574666
Abstract

The result of treatment of children with ITP, who received either 0.5, 1 or 2 mg/kg per day of prednisolone showed that 1 mg/kg per day gave the best response, the least failure rate and the duration of treatment was not different compared to 2 mg/kg per day. It was concluded that the proper dosage of the prednisolone given to these children should be 1 mg/kg per day. However the number of the patients in the study were rather small further clinical studies and treatment with 1 mg/kg and 2 mg/kg per day of prednisolone in childhood ITP are warranted.

摘要

对患有免疫性血小板减少症(ITP)的儿童进行治疗,这些儿童每天接受0.5、1或2毫克/千克泼尼松龙治疗,结果表明,每天1毫克/千克的治疗效果最佳,失败率最低,且与每天2毫克/千克相比,治疗持续时间没有差异。得出的结论是,给予这些儿童泼尼松龙的合适剂量应为每天1毫克/千克。然而,该研究中的患者数量相当少,因此有必要对儿童ITP进一步开展临床研究,并采用每天1毫克/千克和2毫克/千克泼尼松龙进行治疗。

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