Vannas A, Setälä K, Ruusuvaara P
Acta Ophthalmol (Copenh). 1977 Dec;55(6):951-8. doi: 10.1111/j.1755-3768.1977.tb05676.x.
The clinical specular microscope has made it possible to study corneal endothelial cells in vivo. In this study we report for the first time cell densities of unilateral glaucoma patients compared to the normotensive control eyes of the same patient. The corneal endothelium of 27 unilateral capsular glaucoma patients was photographed with a clinical specular microscope. The endothelial cell density was lower in the affected eye than in the normotensive fellow eye in 15 cases. In 10 patients the cell density was the same in both eyes. In two cases the glaucoma eye had a higher density than the fellow eye. Comparison of the above groups showed a statistical difference in the number of glaucoma eyes with a lower cell density (15 lower against 2 higher). The endothelial cell density could not be correlated with the duration of treatment of severity of the glaucoma.
临床镜面显微镜使在活体状态下研究角膜内皮细胞成为可能。在本研究中,我们首次报告了单侧青光眼患者与同一患者的正常眼压对照眼的细胞密度情况。用临床镜面显微镜对27例单侧囊膜性青光眼患者的角膜内皮进行拍照。15例患者患眼的内皮细胞密度低于正常眼压的对侧眼。10例患者双眼的细胞密度相同。2例患者青光眼患眼的细胞密度高于对侧眼。上述几组比较显示,细胞密度较低的青光眼患眼数量存在统计学差异(15例较低对2例较高)。内皮细胞密度与青光眼治疗时间或严重程度无关。