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行军性血红蛋白尿症中的低血浆触珠蛋白。

Low plasma haptoglobin in march haemoglobinuria.

作者信息

Payne R B

出版信息

J Clin Pathol. 1966 Mar;19(2):170-2. doi: 10.1136/jcp.19.2.170.

DOI:10.1136/jcp.19.2.170
PMID:5909699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473223/
Abstract

A student had haemoglobin in the urine after running but not after cycling. The haemoglobinuria was related to the hardness of the surface on which he ran and to his running style. The concentration of haptoglobin in his plasma was less than normal. This was most pronounced after he had been running, when haptoglobin had combined with free haemoglobin, but the concentration was also low when there had been no haemolysis for six weeks. Thus two factors combined to give him haemoglobinuria: lysis of red cells by mechanical damage and lack of haptoglobin to combine with liberated haemoglobin.

摘要

一名学生跑步后尿液中出现血红蛋白,但骑自行车后则没有。血红蛋白尿与他跑步的地面硬度以及跑步方式有关。他血浆中触珠蛋白的浓度低于正常水平。这在他跑步后最为明显,此时触珠蛋白已与游离血红蛋白结合,但在六周没有溶血的情况下,其浓度也很低。因此,有两个因素共同导致了他出现血红蛋白尿:机械损伤导致红细胞溶解以及缺乏触珠蛋白来结合释放出的血红蛋白。

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Low plasma haptoglobin in march haemoglobinuria.行军性血红蛋白尿症中的低血浆触珠蛋白。
J Clin Pathol. 1966 Mar;19(2):170-2. doi: 10.1136/jcp.19.2.170.
2
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Biochemical changes in a 100 km run: proteins in serum and urine.100公里跑中的生化变化:血清和尿液中的蛋白质
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本文引用的文献

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Paroxysmal Hæmoglobinuria of Traumatic Origin.创伤性阵发性血红蛋白尿
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A spectrophotometric method for quantitating hemoglobin in plasma or serum.一种用于定量测定血浆或血清中血红蛋白的分光光度法。
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[March hemoglobinuria (Studies on the mechanism of hemolysis and review of the literature)].[行军性血红蛋白尿(溶血机制研究及文献综述)]
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EXERTIONAL HAEMOGLOBINURIA: A REPORT ON THREE CASES WITH STUDIES ON THE HAEMOLYTIC MECHANISM.运动性血红蛋白尿症:三例报告及溶血机制研究
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Familial hypohaptoglobinemia. A genetically determined trait segragating from glucose-6-phosphate dehydrogenase deficiency.家族性低触珠蛋白血症。一种与葡萄糖-6-磷酸脱氢酶缺乏症分离的由基因决定的性状。
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