Schneider C H
Pathol Microbiol (Basel). 1975;42(4):254-66.
A number of chemically definable parameters related to antigenicity are discussed. These include determinant size and density, antigen shape as well as eliciting, inhibiting and tolerogenic capacities of model antigens, notably those of the penicillin allergy model. A kinitic argument for a restricted antibody diversity is presented.
讨论了一些与抗原性相关的化学可定义参数。这些参数包括决定簇大小和密度、抗原形状以及模型抗原的激发、抑制和致耐受性能力,特别是青霉素过敏模型的那些参数。提出了一个关于有限抗体多样性的动力学观点。