Knoke M, Bernhardt H
Z Gesamte Inn Med. 1977 Aug 15;32(16):suppl 251-2.
From the practical experience and from own results of examinations in the therapy of mycoses of mucous membrane and organ resulted the following problems: It is necessary a sufficient concentration of the antimycotic remedy in the place of the growth of the fungus on and in the tissues. It depends on the kind of application, absorptive capacity and compatibility. When pre-disposing factors are present the gastrointestinal tract should be cleaned up as the most important reservoir. Repeated determinations of the causative organisms and tests of the resistance are necessary for therapy.
在真菌在组织内外生长的部位,抗真菌药物必须有足够的浓度。这取决于给药方式、吸收能力和耐受性。当存在诱发因素时,胃肠道作为最重要的菌库应进行清理。治疗过程中需要反复测定病原体并进行耐药性检测。