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西非雨林高度流行村庄中盘尾丝虫的虫负荷量

Worm burden of onchocerca volvulus in a hyperendemic village of the rain-forest in West Africa.

作者信息

Schulz-Key H, Albiez E J

出版信息

Tropenmed Parasitol. 1977 Dec;28(4):431-8.

PMID:601852
Abstract

During a study on the effects of nodulectomy on onchocerciasis in a village in the Liberian rain-forest 400 Onchocerca-nodules were excised from 34 inhabitants. The analysis of the nodules revealed a worm burden of 718 complete live male and 1062 complete live female worms as well as 9 male and 117 female worms which were mostly calcified and degenerating. 73% of the live females contained developing embryos or released microfilariae, the other females either contained eggs or showed empty uteri. Some observations were made on degenerating worms. The male:female sex ratio was 1:1.5 and possible reasons for this are discussed.

摘要

在利比里亚雨林某村庄进行的一项关于结节切除术对盘尾丝虫病影响的研究中,从34名居民身上切除了400个盘尾丝虫结节。对这些结节的分析显示,虫负荷包括718条完整的活雄虫和1062条完整的活雌虫,以及9条雄虫和117条雌虫,后者大多已钙化并正在退化。73%的活雌虫含有发育中的胚胎或释放出微丝蚴,其他雌虫要么含有虫卵,要么子宫为空。对正在退化的虫体进行了一些观察。雄雌性别比为1:1.5,并对其可能的原因进行了讨论。

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Tropenmed Parasitol. 1977 Dec;28(4):431-8.
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引用本文的文献

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Assessing Intensity of Infection and Genetic Diversity Using Mitochondrial Genome Sequencing of Single Microfilariae Obtained before and after Ivermectin Treatment.利用伊维菌素治疗前后获得的单个微丝蚴的线粒体基因组测序评估感染强度和遗传多样性。
Pathogens. 2023 Jul 24;12(7):971. doi: 10.3390/pathogens12070971.
2
[Treatment of onchocerciasis in hyperendemic communities in West Africa with small, gradually increasing doses of suramin. 1. Parasitological results and ophthalmological surveillance in a region where transmission has not been interrupted].[在西非高度流行社区采用小剂量、逐渐增加剂量的苏拉明治疗盘尾丝虫病。1. 未阻断传播地区的寄生虫学结果及眼科监测]
Bull World Health Organ. 1980;58(6):917-22.
3
[Treatment of onchocerciasis with low, increasing doses of suramin in hyperendemic communities of Western Africa: 2. Clinical parasitologic and ophthalmologic results in a zone where transmission is controlled].
[在西非高度流行社区使用低剂量递增剂量苏拉明治疗盘尾丝虫病:2. 传播得到控制地区的临床、寄生虫学和眼科结果]
Bull World Health Organ. 1984;62(2):261-9.