Fekete M, Horváth M, Bárdosi L, Mestyán J
Acta Paediatr Acad Sci Hung. 1977;18(1):53-9.
A significant rise in the frequency of neonatal pulmonary haemorrhage was observed in the year when intensive oxygen therapy by CPAP and IPPV ventilation was started. To clarify the role of oxygen therapy the neonatal deaths occurring in two periods of different oxygen treatment were analysed and compared in respect of all clinical features which may be involved in the pathogenesis of pulmonary haemorrhage. In conclusion it is suggested that the local effect of oxygen is probably an additional but significant pathogenetic factor in the condition.
在开始采用持续气道正压通气(CPAP)和间歇正压通气(IPPV)进行强化氧疗的那一年,观察到新生儿肺出血的发生率显著上升。为了阐明氧疗的作用,分析并比较了在两个不同氧疗时期发生的新生儿死亡病例,涉及所有可能与肺出血发病机制有关的临床特征。总之,提示氧的局部作用可能是该病一个额外但重要的发病因素。