Palmer J K, Roberts J B
Science. 1967 Jul 14;157(3785):200-1. doi: 10.1126/science.157.3785.200.
2-Mercaptobenzothiazole is an exceptionally potent inhibitor of banana polyphenoloxidase; it significantly delays the onset of substrate oxidation at concentrations as low as 10(-7)M and causes prolonged inhibition at 2 x 10(-5)M or higher. Inhibition results from formation of a dissociable, mixed complex between the enzyme and the inhibitor.
2-巯基苯并噻唑是香蕉多酚氧化酶的一种极其有效的抑制剂;在低至10^(-7)M的浓度下,它能显著延迟底物氧化的开始,并在2×10^(-5)M或更高浓度时导致长时间抑制。抑制作用源于酶与抑制剂之间形成可解离的混合复合物。