Loggini F, Milici G, Grillo O C
Ann Sclavo. 1977 May-Jun;19(3):464-9.
The Authors have carried out a research on the purpose of explain the action of a typhoid vaccines prepared on a semi-synthetic medium, which in preliminary tests on mice and men evinced good immunizing power. The tests now performed demonstrate that an acellular filtrate of the vaccine (obtained from 24 h old culture) showed have the characteristics of an exotoxin and developes a strong immunizing power.