马来西亚人群中的遗传标记：尿苷单磷酸激酶（UMPK）、磷酸乙醇酸磷酸酶（PGP）和胰腺淀粉酶（AMY2）的变体

Genetic markers in a Malaysian population: variants of uridine monophosphate kinase (UMPK), phosphoglycolate phosphatase (PGP) and pancreatic amylase (AMY2).

作者信息

Zarinah K H, Abdullah F, Tan S G

出版信息

Ann Hum Biol. 1984 Nov-Dec;11(6):533-6. doi: 10.1080/03014468400007441.

Abstract

Three genetic markers, red-cell UMPK, PGP and serum AMY2 were investigated in Malaysians of Malay, Chinese and Indian ancestries using starch-gel and agarose-gel electrophoresis. UMPK was found to be polymorphic in all three races. Variants were observed for PGP in Malays; in Indians it is a polymorphic marker whereas it is monomorphic in Chinese. AMY2 was polymorphic only in Indians. The UMPK1 frequencies in Malays, Chinese and Indians, respectively, are 0.851, 0.880 and 0.942. The PGP1 frequencies are 0.991, 1.000, 0.962, and the AMY1(2) frequencies are 1.000, 1.000 and 0.983.

摘要

利用淀粉凝胶和琼脂糖凝胶电泳技术，对具有马来、中国和印度血统的马来西亚人研究了三种遗传标记，即红细胞UMPK、PGP和血清AMY2。发现UMPK在所有三个种族中均具有多态性。在马来人中观察到PGP的变异；在印度人中它是一个多态性标记，而在中国人群中它是单态的。AMY2仅在印度人中具有多态性。马来人、中国人和印度人中UMPK1的频率分别为0.851、0.880和0.942。PGP1的频率分别为0.991、1.000、0.962，AMY1(2)的频率分别为1.000、1.000和0.983。