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[锝 Tc 99m 焦磷酸盐闪烁扫描术在心绞痛中与垂体 - 肾上腺系统活性相关的指标]

[Indicators of scintigraphy using technetium Tc 99m pyrophosphate in angina pectoris in relation to the activity of the pituitary-adrenal system].

作者信息

Vinogradov A V, Rylova A K, Sycheva I M, Lobzeva V I

出版信息

Kardiologiia. 1984 Oct;24(10):12-5.

PMID:6097735
Abstract

The effect of exercise on the parameters of the scintigraphy of the myocardium with labelled pyrophosphate was studied in 35 patients with coronary heart disease and angina of effort and at rest with regard to the activity of the pituitary-adrenal cortex system. The functional status of this system was evaluated on the basis of data on the blood changes in somatotrophic hormone and cortisol. The use of a scoring system made it possible to identify four types of the pattern of the scintigraphic parameters. Type I and II of the pattern of the scintigraphic parameters indicating the normal ratios between the requirements of the cardiac muscle in oxygen and myocardial perfusion were characteristic of the patients with angina pectoris in the presence of an increased activity of the pituitary-adrenal cortex system. When the coronary heart disease patients with angina had a lower activity of this system, the authors more frequently recorded types III and IV of the pattern of scintigraphy which reflected a decreased perfusion and myocardial damage during exercise.

摘要

在35例冠心病患者以及劳力性和静息性心绞痛患者中,就垂体-肾上腺皮质系统的活性,研究了运动对标记焦磷酸盐心肌闪烁扫描参数的影响。该系统的功能状态根据生长激素和皮质醇血液变化的数据进行评估。使用评分系统能够识别闪烁扫描参数模式的四种类型。闪烁扫描参数模式的I型和II型表明心肌对氧的需求与心肌灌注之间比例正常,这在垂体-肾上腺皮质系统活性增加的心绞痛患者中较为典型。当伴有心绞痛的冠心病患者该系统活性较低时,作者更常记录到闪烁扫描模式的III型和IV型,这反映了运动期间灌注减少和心肌损伤。

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