Hoyme U B, Hermann P E, Gerth H J
Geburtshilfe Frauenheilkd. 1984 Dec;44(12):796-802. doi: 10.1055/s-2008-1036522.
Microbiological examinations were performed in 247 women complaining of vaginal discharge. An average of 3.9 different organisms was isolated from each patient. Gardnerella vaginalis was found in 62.8% of all women. Candida spp. were seen in 22.7%. Trichomonas vaginalis occurred in 6.5%, Neisseria gonorrhoeae in 1.2%, Chlamydia trachomatis in 10.1%, Mycoplasmata in 13.8%, Cytomegalovirus in 2.8%, and Herpes simplex Type 2-virus in 1.1%. None of the above was found in 17.4% of the patients. Statistic evaluation revealed correlation between different pathogens and between pathogens and normal vaginal bacteria, e.g. a higher prevalence of Trichomonas vaginalis, Mycoplasmata and Bacteroides spp. in association with Gardnerella vaginalis, and a lower prevalence of Candida spp. and lactobacilli. A pathogenic role of the Mycoplasmata in connection with vaginal discharge cannot be supported by this study. The results of antimicrobial therapy are reported and discussed.
对247名主诉有阴道分泌物的女性进行了微生物学检查。每位患者平均分离出3.9种不同的微生物。在所有女性中，62.8%发现了阴道加德纳菌。念珠菌属在22.7%的患者中被发现。阴道毛滴虫的发生率为6.5%，淋病奈瑟菌为1.2%，沙眼衣原体为10.1%，支原体为13.8%，巨细胞病毒为2.8%，单纯疱疹病毒2型为1.1%。17.4%的患者未发现上述任何一种微生物。统计学评估显示不同病原体之间以及病原体与正常阴道细菌之间存在相关性，例如，阴道毛滴虫、支原体和拟杆菌属与阴道加德纳菌同时存在时的患病率较高，而念珠菌属和乳酸杆菌的患病率较低。本研究无法支持支原体与阴道分泌物有关的致病作用。报告并讨论了抗菌治疗的结果。
