Savarino V, Mansi C, Picciotto A, De Conca V, Testa R, Santi R, Dodero M, Celle G
Quad Sclavo Diagn. 1980 Dec;15(4):1090-6.
In order to determine the value of serum Gamma-glutamyltranspeptidase in the diagnosis of secondary hepatic malignancy, the variations of the serum measurement of different hepatic enzymes have been studied in 160 patients, 80 of which have hepatic metastases gamma GT showed an increase in 95% of the patients with metastases even if there has been a high percentage of false-positive results in the control patients and in those who were carriers of cancer without hepatic metastases. The Authors, after having briefly discussed the meaning of the false positivity rate, conclude that such an enzyme proves once to be a simple and sensitive test of secondary hepatic malignancy and that further studies will help to make it more specific.
为了确定血清γ-谷氨酰转肽酶在继发性肝恶性肿瘤诊断中的价值,对160例患者不同肝酶的血清检测变化进行了研究,其中80例有肝转移。γ-谷氨酰转肽酶在95%的转移患者中升高,即使在对照患者以及有癌症但无肝转移的患者中假阳性结果比例较高。作者在简要讨论了假阳性率的意义后得出结论,这种酶被证明是继发性肝恶性肿瘤的一种简单而敏感的检测方法,进一步的研究将有助于使其更具特异性。