Leucocyte phagocytic response in relation to abo blood groups.

In vitro suspension technique was carried out in order to study the phagocytic activity of the leucocytes spun out from the blood of healthy young volunteers belonging to similar socio-economic group and having no history of recurrent infection, drug medication and chronic smoking. Saline suspension of Staphylococcus aureus was mixed with leucocyte rich cream and incubated at 37 degrees C for 1/2 hr. Films were stained with Leishman and leucocytes were examined under microscope for calculation of their phagocytic coefficients. Blood group O seems to have highest values, followed by A, B and AB in that order. It is likely that the phagocytic co-efficient is correlated to the presence or absence of specific blood group substances ABH (O) or their antibodies.