海鸟肝脏微粒体单加氧酶及其与有机氯污染物关系的研究。
A study of the hepatic microsomal monooxygenase of sea birds and its relationship to organochlorine pollutants.
作者信息
Knight G C, Walker C H
出版信息
Comp Biochem Physiol C Comp Pharmacol. 1982;73(1):211-21. doi: 10.1016/0306-4492(82)90193-9.
PMID:6128175
Abstract
- The levels of hepatic microsomal monooxygenase in sea birds were determined using organochlorine substrates. Levels of cytochrome P450 and organochlorine residues were also measured. 2. The razorbill (Alca torda) and puffin (Fratercula arctica) showed highly variable activities which were resolved into multiple peaks on frequency diagrams. 3. The most active individuals amongst razorbills were early season females with large ovaries. 4. The properties of monooxygenase from individuals of low and high activity were compared. 5. The results are discussed in relation to PCB pollution.
摘要
- 使用有机氯底物测定海鸟肝脏微粒体单加氧酶的水平。还测量了细胞色素P450水平和有机氯残留量。2. 刀嘴海雀（Alca torda）和海鹦（Fratercula arctica）表现出高度可变的活性，在频率图上可分解为多个峰值。3. 刀嘴海雀中活性最高的个体是卵巢较大的繁殖季节早期雌性。4. 比较了低活性和高活性个体的单加氧酶特性。5. 结合多氯联苯污染对结果进行了讨论。
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