Woo N H, Roe B A, Rich A
Nature. 1980 Jul 24;286(5771):346-51. doi: 10.1038/286346a0.
The crystal structure of Escherichia coli tRNAfMet an initiator transfer RNA, has been determined. While grossly similar to that of the chain-elongating yeast tRNAPhe, there are three major differences. One involves the folding of the anticodon loop; in particular, the position of the constant uridine, U33. This difference was unexpected and may be of functional significance.
大肠杆菌起始转运核糖核酸tRNAfMet的晶体结构已被确定。虽然它与链延伸的酵母苯丙氨酸tRNA在总体上相似,但存在三个主要差异。其中一个涉及反密码子环的折叠;特别是恒定尿苷U33的位置。这种差异出乎意料,可能具有功能上的重要性。