结膜和角膜的 spheroid 变性。两年随访

Spheroid degeneration of conjunctiva and cornea. Two years' follow up.

作者信息

Norn M

出版信息

Acta Ophthalmol (Copenh). 1980 Oct;58(5):805-11. doi: 10.1111/j.1755-3768.1980.tb06694.x.

DOI:10.1111/j.1755-3768.1980.tb06694.x

Abstract

Twenty-six subjects with spheroid degeneration were followed up after two years. The number of colourless conjunctival droplets was seen to have increased by on an average 46% (2 alpha = 0.05) and that of autofluorescent conjunctival droplets by 223% (2 alpha less than 0.01). Counting within the individual sites sites disclosed that some droplets will disappear (not less than 30 and 21% respectivelY), while recently formed will constitute at least 76 and 243%. The number of areas with band-shaped keratopathy was found to rise from 3 to 26 (P less than 0.001) out of 104 possibilities, (nasally and temporally of right and left eye). Vital staining (fluorescein, rose bengal, tetrazolium, alcian blue) showed the epithelium above the droplets to be intact, and the droplet-containing eyes were found not to be abnormally dry (break up time, tear production).

摘要

对26名患有球体退变的受试者进行了两年的随访。无色结膜微滴数量平均增加了46%（双侧α=0.05），自发荧光结膜微滴数量增加了223%（双侧α<0.01）。在各个部位计数发现，一些微滴会消失（分别不少于30%和21%），而新形成的微滴至少占76%和243%。在104个可能出现带状角膜病变的区域（左右眼的鼻侧和颞侧）中，发现出现带状角膜病变的区域数量从3个增加到26个（P<0.001）。活体染色（荧光素、孟加拉玫瑰红、四氮唑、阿尔辛蓝）显示微滴上方的上皮完整，且含有微滴的眼睛未发现异常干燥（泪膜破裂时间、泪液分泌）。