[猪白细胞干扰素在不同细胞培养物上的种属特异性研究]
[Species specificity study of swine leukocyte interferon on different cell cultures].
作者信息
Pokidysheva L N, Lavrukhina L A
出版信息
Vopr Virusol. 1980 Nov-Dec(6):676-8.
PMID:6164162
Abstract
The antiviral effect of swine leukocyte interferon was studied in cell cultures of different origins. Swine leukocyte interferon was demonstrated to protect human diploid fibroblasts. The cultures of primarily trypsinized mouse embryo fibroblasts and continuous bovine embryo tracheal cells are as sensitive to swine leukocyte interferon as human diploid cells. Studies of the age sensitivity of mouse fibroblast tissues to swine interferon showed the tissue sensitivity to interferon to decline markedly with age.
摘要
在不同来源的细胞培养物中研究了猪白细胞干扰素的抗病毒作用。已证明猪白细胞干扰素可保护人二倍体成纤维细胞。原代胰蛋白酶消化的小鼠胚胎成纤维细胞和连续的牛胚胎气管细胞培养物对猪白细胞干扰素的敏感性与人二倍体细胞相同。对小鼠成纤维细胞组织对猪干扰素的年龄敏感性研究表明，组织对干扰素的敏感性随年龄显著下降。
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